Tuesday, May 8, 2012
NSAIDS and Renal Cancer
Incidentally detected kidney masses are increasing in frequency as more and more Americans undergo CT scans, MRIs, and ultrasounds for a variety of conditions. Historically, renal cell cancer was presented with flank pain, mass, or blood in the urine. However, as medical imaging has improved in its detection, and its use has flourished, lesions are becoming quite common.
While not all lesions are cancerous, this is the obvious concern. Risks for kidney cancer include smoking and hypertension; however, not all patients with these lesions have these risk factors.
Recently, a study was published showing that chronic and frequent use of nonaspirin anti-inflammatory (NSAID) use was associated with an increased risk of renal cancer development. While factors such as smoking and hypertension could confound these results, this increased risk may be a partial factor in the increasing incidence of these lesions.