Saturday, June 23, 2012
Hope for Peyronie's Disease
Peyronie’s disease, a disease effecting 10% of men, results from collagen deposits in the tunica albuginea of the penis. These deposits, which are the result of trauma to the penis during intercourse, lead to scarring and curvature of the penis. This curvature can be quite painful and may prevent successful intercourse.
Multiple medications, ranging from Vitamin E to injectable Verapamil, have been tried to help reverse this curvature. However, successful outcomes have been few and far between. As a result, urologists typically recommend surgical procedures to correct the curvature. Yet, as scarring can continue or recur, the results may also be poor.
In good news for men with this condition, Xiaflex (Auxilium Pharmaceuticals), a drug currently used to treat Dupuytren’s contracture (a disfiguring disease of the hands due to collagen deposition), has shown success in improving penile curvature. While only in preliminary studies and not currently FDA approved, improved penile curvature was seen at 36 weeks of study with few side effects.
For a disease with little support, it seems help may be on the way.